The General Data Protection Regulation (GDPR), aka EU Regulation 2016/679, unifies data protection for all residents of the European Union (EU) as of May 25, 2018. Additionally, GDPR also addresses the export and processing of personal data outside the EU, which is where cloud users are getting concerned around compliance.
Battle the Dark Side of Data Governance from DATAVERSITY To view the On Demand recording from this presentation, click HERE>> This webinar was sponsored by: About the Webinar On May 25th, 2018, Star Wars fans will enjoy a new movie while organizations world-wide must protect their EU customers? data or risk the high penalties of [?]
To view just the slides from this presentation, click HERE>> This webinar was sponsored by: About the Webinar On May 25th, 2018, Star Wars fans will enjoy a new movie while organizations world-wide must protect their EU customers? data or risk the high penalties of non-compliance. Regulations such as SOX, HIPAA, and GDPR bring about [?]
by Angela Guess According to a recent press release, ?The European Union?s forthcoming General Data Protection Regulation (GDPR) will reshape the rules of data management and raise both the cost of complying with laws governing people?s personal data and the risks and considerable financial liabilities involved in mishandling it. The rule has implications across the [?]
Click to learn more about authoráDean Yao. According to a recent Forbes article, successful businesses will share ?a deliberate choice in favor of leveraging Open Source technologies at the heart of their modern Data Architecture? in the near future. The article highlights how large companies like GitHub, Ford Motor Company, Macy?s, Progressive Insurance, and Netflix [?]
by Angela Guess A new press release states, ?Symphony Ventures, the global services firm specializing in Intelligent Automation, today announced the launch of a new General Data Protection Regulation (GDPR) compliance capability. Partnering with leading provider of information security and data protection expertise, IT Governance, Symphony will offer global enterprises an end-to-end solution for meeting [?]
People, businesses, and machines are generating data at a staggering pace.áThe business expectation is that you will use this data to gain insight, increase competitive advantage, and become truly data-driven. Data lies at the heart of this digital transformation and is underway at most organizations.
by Angela Guess According to a new press release, ?With less than four months until the May 25 effective date for the European Union?s General Data Protection Regulation (GDPR), a bare 6% of enterprises say they are prepared for the upcoming regulation, reveals a new research report issued today from erwin, Inc. The company?s 2018 [?]
by Angela Guess According to a new press release, ?Edgile, the leading cyber risk and regulatory compliance partner to the Fortune 500, today announced the release of its quarterly iGRC update which adds new state and international sources addressing cybersecurity and privacy compliance to the iGRC content platform. The report added a number of new [?]
Click to learn more about authoráVictor DeMarines. As the May 25, 2018 deadline for the General Data Protection Act (GDPR) regulations inches closer, there isn?t a compliance officer on the planet who isn?t consumed with making sure every asset is covered. With the networked, global nature of our economy, the act is likely to touch [?]
by Angela Guess According to a new press release, ?NICE today announced the release of the GDPR Compliance Center, its groundbreaking mission-specific solution for meeting the requirements of the European Union?s new General Data Protection Regulation (GDPR) in the contact center. The NICE solution streamlines the implementation of mechanisms for the adequate processing of private [?]
I hate writing about politics because the topic is so polarizing. However, I?ve had enough questions about the net neutrality issue that I felt InfoWorld readers needed some preliminary guidance about its effect on enterprise-grade cloud computing.
It?s the morning of May 18, 2018 and you arrive at your desk to find a message from a former job applicant in Germany asking for an inventory of all Personally Identifiable Information (PII) you have for him, and a request to delete all his information. There?s also a notice from IT saying they have [?]
by Angela Guess A new press release states, ?With the General Data Protection Regulation (GDPR) taking effect May 25, 2018, businesses around the globe should be preparing accordingly. However, through a recent survey, Trend Micro Incorporated, a global leader in cybersecurity solutions, found that C-suite executives are not approaching the regulation with the seriousness required, [?]
Natural killer (NK) cells detect and kill virally infected and transformed cells. NK cell activation depends on the balance between signaling by inhibitory and activating receptors, and cytokine signaling can synergize with activating receptor signaling to induce NK cell activation. Mukherjee et al . performed mass cytometry analysis of the abundances of more than 30 proteins and computational analysis of the relationships between those changes in abundance. The authors delineated the mechanism underlying the synergy between signaling by the cytokine interleukin-2 (IL-2) and subsequent stimulation of the activating receptor NKG2D in immature and mature subsets of human NK cells. This analysis predicted and experiments verified that the IL-2?stimulated increase in the abundance of the phosphatase CD45 in immature NK cells was the major determinant of the enhanced responses of these cells to NKG2D stimulation. The application of this type of analysis to other immune cell types will help to discover other synergies underlying cellular activation and function.
The linkage between stress early in life and behavioral depression in adulthood is complex. Pe˝a et al. were able to define a time period in early development when mice are especially susceptible to stress. Mice subjected to stress during this time period were less resilient to stress in adulthood. Genes regulated by the transcription factor orthodenticle homeobox 2 (OTX2) primed the response toward depression in adulthood. Although early stress could establish the groundwork for later depression, that priming could be undone by intervention at the right moment.
Science , this issue p. 
Neural stem cells (NSCs) in specialized niches in the adult mammalian brain generate neurons throughout life. NSCs in the adult mouse ventricular-subventricular zone (V-SVZ) exhibit a regional identity, and depending on their location, generate distinct olfactory bulb interneuron subtypes. Here we show that the hypothalamus, a brain area regulating physiological states, provides long-range regionalized input to the V-SVZ niche and can regulate specific NSC subpopulations. Hypothalamic proopiomelanocortin (POMC) neurons selectively innervate the anterior ventral V-SVZ and promote the proliferation of Nkx2.1+ NSCs and generation of deep granule neurons. Accordingly, hunger and satiety regulate adult neurogenesis by modulating the activity of this hypothalamic-V-SVZ connection. Our findings reveal that neural circuitry, via mosaic innervation of the V-SVZ, can recruit distinct NSC pools allowing on-demand neurogenesis in response to physiology and environmental signals.
Acetylation of histone H4 by the histone acetyltransferase CBP during sepsis switches chromatin to an open state, which enables the expression of genes encoding proinflammatory cytokines. Understanding the regulation of CBP stability could help in the treatment of inflammatory diseases. Wei et al. showed that the E3 ubiquitin ligase subunit FBXL19 ubiquitylated CBP, targeting it for proteasomal degradation. The authors also showed that the deubiquitylase USP14 reversed this process, enhancing CBP stability. Furthermore, signaling by the bacterial product LPS prevented the FBXL19-CBP interaction and enhanced USP14 activity, thus promoting inflammatory cytokine production. Pharmacological inhibition of USP14 led to reduced CBP abundance and decreased cytokine production, suggesting that manipulation of CBP stability may provide a means to control inflammatory responses to infections.
In a world constantly bombarded by ransomware, viruses, and other data breaches, people want to feel that they and their data are protected. As such, the EU?s General Data Protection Regulation (GDPR) compliance law has caused quite the buzz since it was approved in April 2016. In short, GDPR ensures data protection for any EU citizen.
by Angela Guess A new press release reports, ?With one year remaining until the commencement of EU General Data Protection Regulation (GDPR), new research by RiskIQ reveals that more than one-third of all public web pages of FTSE 30 companies capturing personally identifiable information (PII) are in danger of violating the regulation by doing so ?
In many vertebrates, sex of offspring is determined by external environmental cues rather than by sex chromosomes. In reptiles, for instance, temperature-dependent sex determination (TSD) is common. Despite decades of work, the mechanism by which temperature is converted into a sex-determining signal remains mysterious. This is partly because it is difficult to distinguish the primary molecular events of TSD from the confounding downstream signatures of sexual differentiation. We use the Australian central bearded dragon, in which chromosomal sex determination is overridden at high temperatures to produce sex-reversed female offspring, as a unique model to identify TSD-specific features of the transcriptome. We show that an intron is retained in mature transcripts from each of two Jumonji family genes, JARID2 and JMJD3 , in female dragons that have been sex-reversed by temperature but not in normal chromosomal females or males. JARID2 is a component of the master chromatin modifier Polycomb Repressive Complex 2, and the mammalian sex-determining factor SRY is directly regulated by an independent but closely related Jumonji family member. We propose that the perturbation of JARID2/JMJD3 function by intron retention alters the epigenetic landscape to override chromosomal sex-determining cues, triggering sex reversal at extreme temperatures. Sex reversal may then facilitate a transition from genetic sex determination to TSD, with JARID2/JMJD3 intron retention preserved as the decisive regulatory signal. Significantly, we also observe sex-associated differential retention of the equivalent introns in JARID2/JMJD3 transcripts expressed in embryonic gonads from TSD alligators and turtles, indicative of a reptile-wide mechanism controlling TSD.